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Título Bio-instructive scaffolds for musculoskeletal tissue engineering and regenerative medicine.

Publicación London, UK : Academic Press, 2016, c2017.
Descripción física 1 online resource.
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Colección ScienceDirect 2015/16
Contiene: Front Cover; Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine; Copyright; Contents; Contributors; Part I: Introduction; Chapter 1: Bio-Instructive Cues in Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine; 1.1 Introduction; 1.1.1 Role of the Cellular Microenvironment; 1.1.2 Current Challenges; 1.2 The Cellular Microenvironment: Key Aspects; 1.2.1 What is the Microenvironment?; 1.2.2 Components of the Microenvironment; 1.2.2.1 Cells; 1.2.2.2 Soluble Signaling Molecules; 1.2.2.3 Extracellular Matrix
Biochemical Properties of ECM: Molecular Structure and CompositionBiochemical Properties of ECM: Cell-ECM Interactions; Physical Properties of ECM; 1.3 Recapitulation of Cellular Microenvironments With Bioinstructive Scaffolds; 1.3.1 Natural Versus Synthetic Biomaterials; 1.3.2 Engineering Biochemical Properties; 1.3.2.1 Adhesion Ligands; 1.3.2.2 Growth Factors and Cytokines; 1.3.3 Engineering Physical Properties; 1.3.3.1 Mechanics; 1.3.3.2 Anisotropy; 1.3.3.3 Porosity; 1.3.3.4 Topography; 1.3.4 Summary; 1.4 Cellular Detection of the Microenvironment; 1.4.1 Biochemical Signals
1.4.2 Biophysical Signals1.4.2.1 Mechanotransduction; Role of Focal Adhesions; Role of Adherens Junctions; Integrative Pathways of Focal Adhesions and Adherens Junctions; 1.5 Responding to the Microenvironment; 1.6 Conclusion; References; Chapter 2: Functionalizing With Bioactive Peptides to Generate Bio-Instructive Scaffolds; 2.1 Adhesion Molecules; 2.1.1 Adhesion Receptors; 2.1.2 Adhesion Receptor-Binding Peptides; 2.2 Methods of Identifying Cell-Binding Peptides; 2.3 Peptides in Tissue Engineering; 2.3.1 Self-Assembled Peptide Scaffolds; 2.3.2 Cell-Binding Peptides; 2.3.2.1 RGD
2.3.2.2 GFOGER2.3.2.3 REDV; 2.3.2.4 KLPGWSG; 2.3.2.5 DHLSDNYTLDHDRAIH; 2.3.2.6 Summary; 2.4 Conclusion; Acknowledgments; References; Part II: Bone; Chapter 3: Bio-Instructive Scaffolds for Bone Regeneration; 3.1 Introduction; 3.2 Commonly Used Linear Polymers in Bone Tissue Engineering; 3.2.1 Natural Materials; 3.2.1.1 Protein-Based Biomaterials; 3.2.1.2 Polysaccharides-Based Biomaterials; 3.2.2 Synthetic Polymers; 3.2.2.1 Aliphatic Polyesters; 3.2.2.2 Polyalcohols; 3.2.2.3 Other Polyesters; 3.2.2.4 Poly(Amino Acids); 3.2.2.5 Other Linear Polymers; 3.2.3 Hybrid Materials
3.3 Interactions Between Materials and Cells3.3.1 The Effect of Material Morphology on Cells: Geometry Sensing of the Surrounding Network; 3.3.1.1 Porous Scaffolds; 3.3.1.2 Hydrogels; 3.3.1.3 Electrospun Fibers; 3.3.1.4 Pattern; 3.3.2 Other Factors; 3.4 Bioactive Modification of Linear Polymers for Bone Regeneration; 3.4.1 Delivery of Bioactive Substances; 3.4.2 Surface Modification; 3.5 Concluding Remarks; Acknowledgments; References; Part III: Tendon/Ligament; Chapter 4: Bio-Instructive Scaffolds for Tendon/Ligament Regeneration; 4.1 Introduction
Nota Includes index.
Materia Tissue scaffolds.
Regenerative medicine.
Regenerative medicine. (OCoLC)fst01745494
Tissue scaffolds. (OCoLC)fst01762531
Autor secundario Brown, Justin.
Kumbar, Sangamesh.
Banik, Brittany.
OTRO SOPORTE Original 0128033940 9780128033944
ISBN 0128033991 (electronic bk)
9780128033999 (electronic bk)
0128033940
9780128033944